EU- and Horizon-funded consortia spanning cardiac, neurological, orthopedic and rare-disease modeling — alongside dozens of sponsor-led programs in flight.
SMASH-HCM is reshaping the future of Hypertrophic Cardiomyopathy (HCM). The project builds an advanced digital-twin platform combining dynamic biophysical modelling with data-driven intelligence to enable personalised HCM stratification and more effective disease management. Funded by Horizon Europe (GA 101137115), 2024–2027.
DeCODe (Develop Child and Orphan Device Evaluation support) improves healthcare and medical-device development for people with rare diseases and complex conditions, using AI, data-driven methods, and collaborative digital tools to create more personalised and effective care solutions for paediatric and orphan devices. Funded by EU4Health (GA 101160939).
METASTRA is set to transform the way clinicians assess fracture risk in cancer patients with vertebral metastases. The Horizon Europe project provides personalised treatment recommendations based on robust computational models and improved patient stratification. Coordinated by the University of Bologna, METASTRA brings together 15 partners across Europe with €6.7M funding.
SimCardioTest was an international project funded by the European Commission (EU H2020) bringing together 10 organizations from 6 European countries and the United States. It provided new insights into designing predictive tools for cardiac pathologies and accelerated the uptake of computer simulations for testing medicines and medical devices.
Brainteaser was a data science project exploiting big data — health, lifestyle, and environment — to support patients with amyotrophic lateral sclerosis and multiple sclerosis and their clinicians. Using cost-efficient sensors and apps, it integrated large clinical datasets of patient-generated and environmental data.
In Silico World was an EU-funded project involving 14 partner institutions to accelerate the uptake of modelling and simulation technologies for the development and regulatory assessment of medicines and medical devices, developing 11 solutions across osteoporosis, tuberculosis, multiple sclerosis, coronary stenosis, cerebral aneurysms, mammary carcinoma, and covid-19.
Disc4all was a training network advancing integrated computational simulations in translational medicine, applied to intervertebral disc degeneration leading to low back pain — enabling rational interpretation of the complex interactions that lead to symptoms.